Carbenoxolone sodium and deglycyrrhizinated liquorice in gastric ulcer.

Double-blind trial of deglycyrrhizinated liquorice in gastric ulcer.

In order to investigate further the reported beneficial effect of deglycyrrhizinated liquorice in gastric ulcer, a trial with a double-blind, cross-over design was performed. The patients were treated during two consecutive periods of four weeks each with either liquorice extract during the first period and placebo during the second or placebo during the first period and liquorice during the se...

Controlled comparison of cimetidine and carbenoxolone sodium in gastric ulcer.

Fifty-four outpatients with endoscopically diagnosed benign gastric ulcer were allocated at random to treatment with either cimetidine 800 mg daily for six weeks or carbenoxolone sodium 300 mg daily for one week then 150 mg daily for five weeks. Ulcers were reassessed by endoscopy at the end of the trial. The endoscopist was unaware of the treatment and did not take part in the clinical care of...

Treatment of Gastric Ulcer with Carbenoxolone Sodium and Oestrogens.

Effect of low dosage of carbenoxolone sodium on gastric ulcer healing and acid secretion.

Carbenoxolone sodium has been shown to cause significant healing of benign gastric ulcers in three short-term, double-blind clinical trials restricted to ambulant outpatients (Doll, Hill, Hutton, and Underwood, 1962; Doll, Hill, and Hutton, 1965; Doll, Langman, and Shawdon, 1968). The degree of healing in the treated groups was similar to that obtained with inpatient treatment, including bed re...

Carbenoxolone sodium in the treatment of gastric ulcer with special reference to side-effects.